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Biofluids Inc
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Janssen
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Meso Scale Diagnostics LLC
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Image Search Results
Journal: mAbs
Article Title: Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic
doi: 10.1080/19420862.2022.2104153
Figure Lengend Snippet: Comparison of IL-11 reference standard curve performance for (a) “free” human/cyno IL-11 assay on MSD, Simoa HD-1 and SP-X, and (b) “free” mouse IL-11 on MSD and Simoa SP-X, normalized by signal/background.
Article Snippet: The final pairs were transferred to the
Techniques: Comparison
Journal: Alzheimer's & Dementia
Article Title: Repeated plasma p‐tau217 measurements to monitor clinical progression heterogeneity
doi: 10.1002/alz.70319
Figure Lengend Snippet: Between cluster comparison of plasma phosphorylated tau‐217 (p‐tau217) in Cohort 1 and Cohort 2. (A) Cohort 1 and (B) Cohort 2 show between‐cluster comparisons of plasma p‐tau217, with red dots indicating means. Cohort 1 utilized the University of Gothenburg in‐house p‐tau217 assay, whereas Cohort 2 utilized a commercially available kit by Janssen. Both used Quanterix Simoa HD‐X setups. All statistical tests were two‐sided and false‐discovery rate was used to adjust for multiple comparisons in each cohort. Due to differing assays and the range of pg/mL between assays, (D) shows the similarities of mean fold changes for cognitive decline clusters as compared to the stable cognition clusters in both cohorts. (C) Shows steeper plasma p‐tau217 increases over time in slow‐ and rapid‐decline clusters compared to the stable cognition cluster, with 95% confidence intervals. Unstandardized beta coefficients (b) illustrate individual slopes for each cluster. Created in BioRender. Kirsebom, B. (2025) https://BioRender.com/o54z804 .
Article Snippet: In Cohort 2, plasma p‐tau217 concentration was measured using
Techniques: Comparison, Clinical Proteomics